Category: Paper Overviews

Overview: Placebo Stimulants Make You Think You’re Performing Better

TDC abstract: Placebo stimulants are capable of increasing self-reported alertness, focus, and positive mood. These effects are present in the absence of neuropsychological improvement, demonstrating a placebo, likely due to positive expectancies, can make users believe they’re receiving a benefit. Authors: Samantha Lookatch, Hayley Fivecoat, and Todd Moore DOI: 10.1080/02791072.2017.1344897 Link: https://www.ncbi.nlm.nih.gov/pubmed/28699832 Published: July 2017 Background The level of nonmedical […]

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LSD

Overview: LSD’s Subjective Effects Are Highly Reliant on 5-HT2A

Abstract: LSD administration can significantly affect self-related processing in the brain. This was shown by an increase in “meaning” scores for otherwise meaningless music. The effects were correlated with changes in brain regions known to be associated with self-related activity. Most of the effects were blocked by a 5-HT2A antagonist, ketanserin. Authors: Katrin H. Preller, […]

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AMB-Fubinaca

Overview: String of Overdoses from AMB-FUBINACA in New York

Abstract: Dozens of people seemingly overdosed on AMB-FUBINACA, a synthetic cannabinoid, at the same time in July 2016. 18 individuals were taken to local medical centers and no fatalities occurred. Authors: Axel J. Adams, Samuel D. Banister, Lisandro Irizarry, Jordan Trecki, Michael Schwartz, and Roy Gerona DOI: 10.1056/NEJMoa1610300 Link: http://www.nejm.org/doi/full/10.1056/NEJMoa1610300 Published: December 14, 2016 Background Hundreds of […]

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Dictyonema huaorani

Overview: Lichen (Dictyonema huaorani) in Ecuador Might Produce Psychedelic Drugs

Abstract: A lichen growing in Ecuador, Dictyonema huaorani, might produce psychoactive drugs. Among those substances are 5-MeO-DMT and psilocybin (4-PO-DMT). Their presence is not yet definitive, but there is good reason to investigate further. Authors: Michaela Schmull, Manuela Dal-Forno, Robert Lücking, Shugeng Cao, Jon Clardy, and James D. Lawrey DOI: 10.1639/0007-2745-117.4.386 Link: http://www.bioone.org/doi/full/10.1639/0007-2745-117.4.386 Published: November 7, 2014 Introduction Fungi from […]

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mdma

Study Overview: Ecstasy (MDMA) Use In US Sample Of Nightclub & Festival Attendees

Abstract: This paper looks at the rate of MDMA (Ecstasy, Molly) use among young adult nightclub and festival goers. Compared to the general population, people who attend those events have a greater lifetime use rate. Those who take MDMA also report higher rates of drug use overall. Authors: Joseph J. Palamar, Patricia Acosta, Danielle C. Ompad, and Charles M. […]

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DMT

Study Overview: DMT Has Potent Protective Effects Against Hypoxia Via Sigma-1 Receptor Activation

This paper, which was published on September 14, 2016, examines the effect of N,N-Dimethyltryptamine (DMT) on hypoxia-induced cellular changes. It specifically looks at the role of the Sigma-1 receptor. Abstract: DMT is capable of reducing cell death when cells are placed in a hypoxic environment. Sigma-1 receptor activity is involved in that effect. Authors: Attila Szabo, Attila […]

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MDMA pills

Study Overview: Changes In The European MDMA Market

The EMCDDA has released a report which examines recent trends in the MDMA market, with a focus on the European market. Based on their summary of the research in this area, MDMA use is growing, strength has increased, adulterants are less common, and different production methods are taking hold. Research has found the market is adapting to competition and trying […]

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