Etizolam is a benzodiazepine-like drug that provides sedation, euphoria, and anxiety-reduction. It has been used medically in some regions for issues like anxiety, depression, insomnia, and panic disorder.
The substance is currently used by many people in non-medical settings, with etizolam being purchased online.
Most of the issues with the drug arise from excessive sedation, memory loss, and disinhibition. If a high strong+ dose is used or it is combined with other depressants, it could be very physically dangerous.
Etizolam = Etilaam; Depas; Etizest; Sedekopan; Pasaden
Light: 0.5 – 1 mg
Common: 1 – 2 mg
Strong: 2 – 4+ mg
Total: 5 – 8 hours
Onset: 00:20 – 01:00
Experience Reports Erowid References (2016) A fatal intoxication related to MDPV and pentedrone combined with antipsychotic and antidepressant substances in Cyprus. (2016) Etizolam/tizanidine overdose – Consciousness disturbance and myocardial toxicity: case report (2015) Etizolam/pregabalin Fatal intoxication: 2 case reports (2009) Effects of treatment with etizolam 0.5 mg BID on cognitive performance: A 3-week, multicenter, randomized, double-blind, placebo-controlled, two-treatment, three-period, noninferiority crossover study in patients with anxiety disorder (2008) Case report: Etizolam and its major metabolites in two unnatural death cases. (2005) Pharmacokinetics and pharmacodynamics of etizolam are influenced by polymorphic CYP2C19 activity. (2005) Low tolerance and dependence liabilities of etizolam: molecular, functional, and pharmacological correlates. (2004) Inhibition of the metabolism of etizolam by itraconazole in humans: evidence for the involvement of CYP3A4 in etizolam metabolism. (2002) Etizolam-induced superficial erythema annulare centrifugum. (1999) Molecular and neurochemical evaluation of the effects of etizolam on GABAA receptors under normal and stress conditions. (1991) Single and multiple dose pharmacokinetics of etizolam in healthy subjects. (1990) Etizolam in the treatment of generalized anxiety disorder: a double-blind study versus placebo. (1990) Etizolam versus placebo in the treatment of panic disorder with agoraphobia: a double-blind study. (1989) Etizolam in the treatment of generalized anxiety disorder associated with depressive symptoms. (1989) Etizolam in the treatment of generalized anxiety disorder: a controlled clinical trial. Test Results